pro·ger·i·a

(prō-jîr′ē-ə)

A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death before the age of 20. Also called Hutchinson-Gilford progeria syndrome.

[pro- + Greek gēras, old age; see geriatrics + -ia.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

progeria

(prəʊˈdʒɪərɪə)

(Pathology) med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age

[C20: from pro-² + Greek gēras old age]

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pro•ge•ri•a

(proʊˈdʒɪər i ə)

n.

a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person.

[1900–05; < Greek progḗr(ōs) prematurely old (pro- pro-² + -gēros, adj. derivative of gêras old age) + -ia]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

progeria - a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child

abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies

Translations

progeria

n progeria

Mentioned in

References in periodicals archive

He heads the laboratory of regenerative medicine at the Clinical Research Center for Pediatric Hematology, Oncology and Immunology where his research interests include Hutchinson-Gilford Syndrome, new methods of cellular reprogramming, molecular mechanisms of skin and cartilage regeneration and personalized medicine in oncology.

The American Academy of Anti-Aging Medicine (A4m) Adds Alex Zhavoronkov, PhD to List of Featured Keynote Presenters for 22nd Annual World Congress

Progeria (also known as "Hutchinson-Gilford progeria syndrome" and "Hutchinson-Gilford syndrome"1) is a rare and severe genetic condition in which symptoms of aging are manifested at an early age.

KISSCHILD WITH STUNTED GROWTH, BALD HEAD AND BIRD LIKE FACIES

This PA is a new initiative to support research to understand how mutations in the gene for lamin A/C affect nuclear structure, thus leading to bothdysfunction of the nuclear envelope, and depending on the mutation, Hutchinson-Gilford syndrome in humans (Eriksson et al., manuscript in preparation).

The Biological Basis of Hutchinson-Gilford Syndrome (HGS): Relationship to Mutagens in the Lamin A/C Gene (LMNA) and to Other Known Laminopathies. (Fellowships, Grants, & Awards)