In conclusion,
VEGF gene-transfected BMSCs transplantation would be a better therapy for thin endometrium than BMSCs transplantation alone.
cAMP response element binding (CREB), a cellular transcription factor important to angiogenesis, could be activated by
VEGF through phosphorylation of
VEGF receptor 2 (Flk-1) tyrosine kinase.
VEGF is produced in large amounts by the glomerular podocyte and guides endothelial cells in the developing kidney.
The Vascular Endothelial Growth Factor (
VEGF) family are potent angiogenic and vasculogenic growth factors.
Results: In vitro,
VEGF immunohistochemistry stains, HIF-1a and
VEGF protein contents, and the relative expressions of HIF-1a mRNA and
VEGF mRNA in HIF-1a/siRNA group were obviously reduced.
Endothelial cells leave their quiescent state when stimulated by
VEGF and initiate the following steps: basement membrane dissolution, endothelial cell migration and proliferation, capillary tube formation, and the maturation and survival of newly formed vessels.
Keywords: Anredera cordifolia, IL-6;
VEGF; burn wound healing; Pseudomonas aeruginosa
Here we performed an institution-based study on nephrectomy specimens which were histologically diagnosed as RCC and applied IHC to correlate
VEGF and Ki-67 expression with grade and stage of RCC and compare
VEGF expression and Ki-67 labelling index, if any and also discussed their possible utility as tissue-based biomarkers.
The aim of this study was to examine the expression of MUC2 and
VEGF in patients with proven BE.
Bevacizumab (Avastin, Genetech/Roche, USA), a monoclonal antibody against
VEGF which is used off-label to treat various eye diseases, was added to the cultures at a concentration of 0.3125 mg/mL.