Noun | 1. | chancre - a small hard painless nodule at the site of entry of a pathogen (as syphilis) lues, lues venerea, pox, syph, syphilis - a common venereal disease caused by the treponema pallidum spirochete; symptoms change through progressive stages; can be congenital (transmitted through the placenta) sore - an open skin infection deer fly fever, rabbit fever, tularaemia, tularemia, yatobyo - a highly infectious disease of rodents (especially rabbits and squirrels) and sometimes transmitted to humans by ticks or flies or by handling infected animals |