melanocyte-stimulating hormone

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mel·a·no·cyte-stim·u·lat·ing hormone

 (mĕl′ə-nō-sīt′stĭm′yə-lā′tĭng, mə-lăn′ə-)
n. Abbr. MSH
A hormone secreted by the pituitary gland that regulates skin color in humans and other vertebrates by stimulating melanin synthesis in melanocytes and melanin granule dispersal in melanophores. Also called intermedin.
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

MSH

melanocyte-stimulating hormone: a pituitary gland hormone that causes darkening of the skin by increasing the production of melanin.
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.melanocyte-stimulating hormone - a hormone secreted by the anterior pituitary gland that controls the degree of pigmentation in melanocytes
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect
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References in periodicals archive
Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans.
terrestris extract administered orally to C57BL/6J mice resulted in a significantly higher expression of melanocyte-stimulating hormone in the hair follicles of treated mice (75%), compared with that in the control group (18.75%).
The resistance of leptin to leptin receptor in hypothalamus hinders the expression of neuropeptides, namely, POMC and melanocyte-stimulating hormone that regulate energy intake and neuroendocrine functions.
* Stage 1: Binding of melanocyte-stimulating hormone (a-MSH) to the receptor melanocortin 1 receptor (MC1R).
Bremelanotide, which is a melanocortin 4 receptor agonist drug candidate, is a synthetic peptide analog of the naturally occurring hormone alpha-MSH (melanocyte-stimulating hormone).
Global Markets Direct's, 'Melanocyte-Stimulating Hormone Receptor (Melanocortin Receptor 1 or MC1-R or MC1R or MSHR) - Pipeline Review, H1 2016', provides in depth analysis on Melanocyte-Stimulating Hormone Receptor (Melanocortin Receptor 1 or MC1-R or MC1R or MSHR) targeted pipeline therapeutics.
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