prion

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pri·on

(prī′ŏn′, prē′-)
n.
A protein particle that is the agent of infection in a variety of neurodegenerative diseases, including bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, and scrapie. Prions are the only known infectious agents that do not contain DNA or RNA. They derive from a normal body protein that becomes irreversibly misfolded, and they proliferate in the body, possibly by acting as a template for further protein misfolding.
[Alteration of pro(teinaceous) in(fectious particle).]
American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

prion

(ˈpraɪən)
n
(Animals) any of various dovelike petrels of the genus Pachyptila of the southern oceans that have a serrated bill
[C19: New Latin, from Greek priōn a saw]

prion

(ˈpriːɒn)
n
(Microbiology) a protein in the brain, an abnormal form of which is thought to be the transmissible agent responsible for certain spongiform encephalopathies, such as BSE, scrapie, Creutzfeldt-Jakob disease, and kuru
[C20: altered from pro(teinaceous) in(fectious particle)]
Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

pri•on

(ˈpri ɒn, ˈpraɪ-)

n.
a tiny proteinaceous particle, likened to viruses and viroids, but having no genetic component, thought to be an infectious agent in bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, and similar encephalopathies.
[1980–85; pr (oteinaceous) + i (nfectious) + -on1]
Random House Kernerman Webster's College Dictionary, © 2010 K Dictionaries Ltd. Copyright 2005, 1997, 1991 by Random House, Inc. All rights reserved.

pri·on

(prē′ŏn)
A particle composed of protein, similar to a virus but lacking DNA or RNA. Prions are thought to be the agent of infection of some diseases of the nervous system.
The American Heritage® Student Science Dictionary, Second Edition. Copyright © 2014 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.prion - (microbiology) an infectious protein particle similar to a virus but lacking nucleic acid; thought to be the agent responsible for scrapie and other degenerative diseases of the nervous system
microbiology - the branch of biology that studies microorganisms and their effects on humans
subatomic particle, particle - a body having finite mass and internal structure but negligible dimensions
Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
Translations
Prion
prioni
prion
プリオン
프리온

prion

n → Prion nt; prion protein → Prion-Protein nt
Collins German Dictionary – Complete and Unabridged 7th Edition 2005. © William Collins Sons & Co. Ltd. 1980 © HarperCollins Publishers 1991, 1997, 1999, 2004, 2005, 2007

prion

n prion or prión m
English-Spanish/Spanish-English Medical Dictionary Copyright © 2006 by The McGraw-Hill Companies, Inc. All rights reserved.
Mentioned in
References in periodicals archive
Among the topics are the function of prion protein and the family member shadoo, the effect of microglial inflammation in prion disease, clinical aspects of human prion diseases, bovine spongiform encephalopathy and scrapie, and chronic wasting disease: the current assessment of transmissibility.
Prions: Current Progress in Advanced Research, 2nd Edition
Sporadic prion diseases are classified according to phenotype as well as the pairing of the prion protein (PrP) genotype at the methionine (M)/valine (V) polymorphic codon 129 and the conformational characteristics of the abnormal or disease-associated PrP (Pr[P.sup.D]).
Variable Protease-Sensitive Prionopathy Transmission to Bank Voles
The term prion was introduced in 1982 by neurologist Stanley B.
The proper handling of CJD-infected patient samples in the pathology laboratory
In the Introduction of the article titled "A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder" [1], the text reading "Creutzfeldt-Jakob disease (CJD) is a rapidly progressive, fatal neurodegenerative disease caused by aggregation of misfolded prion proteins.
Corrigendum to "A Case of Sporadic Creutzfeldt-Jakob Disease Presenting as Conversion Disorder"
Cellular prion protein, Pr[P.sup.C], is a predominantly a-helical soluble glycoprotein which remains attached to the outer membrane of the cells through a glycol-phosphatidyl inositol linkage [1-3].
A Sequence-Dependent DNA Condensation Induced by Prion Protein
Experts say this marks a significant milestone in quest to better understand prion diseases in people, and could eventually aid the development of new therapies.
New Way To Study Brain Disease Uses Neuro-Cells From Stem Cells
Prion levels were measured using a new, highly sensitive test.
Human form of 'mad cow' disease detectable in skin: study
Due to his research potential and interest in the field he was granted PhD fellowship by Prion Research Group, department of Neurology, Georg-August University.
PU organizes seminar on Alzheimer's disease
Susan Lindquist of the Whitehead Institute for Biomedical Research in Cambridge, Mass., and colleagues tested plant proteins for prion power by swapping bits of them into yeast prions.
Prions may help plants remember
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