ser·tra·line

(sûr′trə-lēn′)

A drug of the SSRI class, C₁₇H₁₇Cl₂ N, used in its hydrochloride form primarily to treat depression, obsessive-compulsive disorder, posttraumatic stress disorder, and anxiety.

[ser(otonin) + (te)tra- + (naphtha)l(ene) + (am)ine.]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

sertraline - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft)

Zoloft

selective-serotonin reuptake inhibitor, SSRI - an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

Translations

sertraline

n sertralina

Mentioned in

References in periodicals archive

He was started on sertraline, and the dose was increased about 2 weeks later.

The power of the turkey sandwich

Lundbeck and Otsuka report positive clinical phase II data for the combination treatment of brexpiprazole and sertraline for treatment of PTSD

H. Lundbeck and Otsuka report positive clinical phase II data for the combination treatment of brexpiprazole and sertraline for treatment of PTSD

Although jitteriness/anxiety syndrome is known to be potentially caused by the use of antidepressants in general, it occurs rarely in patients specifically treated with sertraline. In a prior study, Pohl et al.

Jitteriness/Anxiety Syndrome Developing Immediately following Initiation of Oral Administration of Sertraline

Three SSRI antidepressant medications--fluoxetine, sertraline, and escitalopram--produce modest improvements (about 5% to 10%) in standardized depression scores without a significant increase in the risk of suicide-related outcomes (suicidal behavior or ideation) in adolescent patients with major depression of moderate severity.

Q/ Which SSRIs most effectively treat depression in adolescents?

This study presents the case of a 4-year-old healthy child admitted to the paediatric ward for suspected accidental intoxication due to ingestion of narcoleptic drugs (methylphenidate, sertraline and quetiapine), taken on a regular basis by his 8-year-old brother affected by Asperger syndrome.

Segmental hair testing to disclose chronic exposure to psychoactive drugs/Analisis segmentario del pelo para detectar la exposicion cronica a drogas psicoactivas

The study -- conducted in nonhuman primates with brain structures and functions similar to those of humans -- found that the antidepressant sertraline, a selective serotonin reuptake inhibitor (SSRI) marketed as Zoloft, significantly increased the volume of one brain region in depressed subjects but decreased the volume of two brain areas in non-depressed subjects.

Common Antidepressant May Change Brain

Rhodiola rosea versus sertraline for major depressive disorder: A randomised placebo-controlled trial.

Rhodiola compared to sertraline in depression

H, age 33, has completed a course of cognitive-behavioral therapy (CBT) for major depressive disorder (MDD) and is continuing to take sertraline, 50 mg/d.

June poll results

in the early 1990s, sertraline (sertraline dydrochloride) has entered many countries like the US, European countries and Japan to treat dysthymi and has brought in an annual sales value of over 1 billion all over the world.

Report Published: "China Sertraline Market, 2010-2019"

In the literature, there are three case reports about galactorrhea associated with the use of sertraline. Bronzo and Stahl, in a case with major depressive disorder, have reported galactorrhea after a 5-week treatment using sertraline 100 mg/day.

Sertraline induced galactorrhea

rosea) versus sertraline for mild to moderate major depressive disorder.

Rhodiola rosea versus sertraline for major depressive disorder: a randomized placebo-controlled trial