SSRI

(ĕs′ĕs-är-ī′)

Any of a class of drugs, such as fluoxetine or sertraline, that inhibit the reuptake of serotonin by neurons of the central nervous system and are primarily used in the treatment of depression and obsessive compulsive disorder.

[s(elective) s(erotonin) r(euptake) i(nhibitor).]

American Heritage® Dictionary of the English Language, Fifth Edition. Copyright © 2016 by Houghton Mifflin Harcourt Publishing Company. Published by Houghton Mifflin Harcourt Publishing Company. All rights reserved.

SSRI

abbreviation for

(Pharmacology) selective serotonin reuptake inhibitor; any of a class of drugs, including fluvoxamine, paroxetine, fluoxetine (Prozac), and Lustral, that increase concentrations of serotonin in the brain: used in the treatment of depression

Collins English Dictionary – Complete and Unabridged, 12th Edition 2014 © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003, 2006, 2007, 2009, 2011, 2014

SSRI

Selective Serotonin Reuptake Inhibitor: any of several drugs that inhibit the reabsorption of serotonin by nerve cells, leading to more serotonin activity in the brain: used chiefly as an antidepressant.

[1985–90]

ThesaurusAntonymsRelated WordsSynonymsLegend:

Noun

SSRI - an antidepressant drug that acts by blocking the reuptake of serotonin so that more serotonin is available to act on receptors in the brain

selective-serotonin reuptake inhibitor

antidepressant, antidepressant drug - any of a class of drugs used to treat depression; often have undesirable side effects

fluoxetine, fluoxetine hydrocholoride, Prozac, Sarafem - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade names Prozac or Sarafem); it is thought to work by increasing the activity of serotonin in the brain

paroxetime, Paxil - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Paxil)

sertraline, Zoloft - a selective-serotonin reuptake inhibitor commonly prescribed as an antidepressant (trade name Zoloft)

Mentioned in

References in periodicals archive

* if there is no response, or if the depression is moderate or severe, add an SSRI

Storm in a teacup or cause for concern--SSRIs, youth and suicidality

Research suggests that some SSRIs are associated with an increased risk of suicidal behaviour and thoughts.

Prozac & therapy OK for Europe kids

Currie also points out that two-thirds of SSRI users are women.

Widespread use of SSRI antidepressants drives soaring health care costs in Canada: from women and health protection

DRUG PATROL Reports of adults whose suicidal thoughts and behaviors emerged or worsened during SSRI treatment began to appear in medical journals in 1990.

Prescription for controversy: medications for depressed kids spark scientific dispute

The SSRI drugs showed a faster reduction in suicide risk than the older types and the suicide risk was higher for people before the drug was started.

Dr Scott's surgery

For example, Bostwick and Jaffee prescribed buspirone to four patients after the SSRI sertraline had induced bruxism.

Selective serotonin reuptake inhibitors (SSRI) and bruxism

"This is great news for those patients currently taking an SSRI," states president William Taylor.

SSRI patients are targeted by Synthon

However, he expressed concern that the FDA action is not enough: "The risk of SSRI-induced suicide affects both children and adults," Vickery said, "and although [British regulators] and the FDA have focused on self-directed acts of violence, these drugs can also trigger aggressive acts toward other people." He noted that these risks apply to 'all the SSRI drugs, not just Paxil.

New data show Paxil may increase suicide risk in children

Nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen, when taken on a regular basis, can combine with the SSRIs to cause dangerous gastrointestinal (GI) bleeding in some patients.

Pain relievers don't mix well with antidepressants

During the inquest Plaid Cymru AM Leanne Wood raised concerns with the SSRI drug, saying: ``People can become suicidal when they come off this drug.

DEATH RIDDLE OF AM'S BOYFRIEND

Dr Misra said psychiatrists rarely prescribe tricyclics now because a newer class of drugs called SSRI - which includes Prozac and Seroxat - is available.

Taking these tablets can kill a man

Some patients who discontinue an SSRI (particularly paroxetine) experience a withdrawal syndrome that is characterized by a type of vertigo that occurs in association with visual tracking and is described as visual lag.

Panic disorder in otolaryngologic practice: A brief review. (Special Contribution)