tumour necrosis factor

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Noun1.tumour necrosis factor - a proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis)
TNF, tumor necrosis factor
cytokine - any of various protein molecules secreted by cells of the immune system that serve to regulate the immune system
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References in periodicals archive
Efficacy of tumour necrosis factor blockers in reducing uveitis flares in patients with spondylarthropathy: a retrospective study.
Recurrent uveitis under golimumab treatment in a patient diagnosed with axial spondyloarthritis: Is it a paradoxical effect?
Tumour necrosis factor alpha (TNF-a) is a potential regulator of inflammation and leukocyte activities.
ANALYSIS OF TNF-a GENE EXPRESSION WITH LIPOPOLYSACCCHARIDE (LPS) AND POLYINOSINIC; POLYCYTIDYLIC ACID (POLY I.C) STIMULATION IN HEAD KIDNEY AND SPLEEN OF CIRRHINUS MRIGALA
Tumour necrosis factor (TNF) gene polymorphism influences TNF-alpha production in lipopolysaccharide (LPS)-stimulated whole blood cell culture in healthy humans.
Tumor necrosis factor alpha gene polymorphism and association with its serum level in Iranian population with rheumatoid arthritis
Tumour necrosis factor inhibitors in ankylosing spondylitis.
Acute lymphoid leukemia after anti-TNF-alpha treatment: a case report and review of the literature
It was reported yesterday that the collaboration is aimed at Inhibrx's novel glucocorticoid-induced tumour necrosis factor receptor antibody programme, which is presently at lead selection stage.
Five Prime Therapeutics signs strategic research collaboration and license agreement with Inhibrx
Single base polymorphism in the human tumour necrosis factor alpha (TNF alpha) gene detectable by NcoI restriction of PCR product.
Association between tumor necrosis factor-[alpha]-308 G/A polymorphism and multiple sclerosis: a systematic review and meta-analysis
Wilcock, "Protein and gene expression of tumour necrosis factor receptors I and II and their promoter gene polymorphisms in Alzheimer's disease," Experimental Gerontology, vol.
Polymorphisms in the tumor necrosis factor receptor genes affect the expression levels of membrane-bound type I and type II receptors
Cazlaris et al., "Transgenic mice expressing human tumour necrosis factor: a predictive genetic model of arthritis," EMBO Journal, vol.
Immunological reaction in TNF-[alpha]-mediated osteoclast formation and bone resorption in vitro and in vivo
One such protein is a tumour necrosis factor, which is involved in cell death and can trigger the production of another problematic protein, called MAP4K4, which blocks the formation of insulin when cells are under adverse conditions.
Genetic material that enhances insulin production identified
Tumour necrosis factor (TNF) is prominent among them.
Tumour necrosis factor neutralization in MS: a cautionary tale
In 2008, Nice said patients would not able able to try a second anti-TNF (tumour necrosis factor alpha inhibitor) if their first attempt at anti-TNF therapy failed.
Relief for arthritics as health watch dog u-turns on drugs
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