Professor of Oral Pathology Tuula Salo investigates oral cancer and especially the interaction between
cancer cells and their surrounding tissue.
A major "don't eat me" signal which
cancer cells appear to use to stop the immune system from attacking them has been discovered by US researchers.
The study explores this communication between precancerous and
cancer cells in the context of an enzyme called PI3K.
According to Cancer Research UK, cancer can come back if treatment failed to get rid of all the
cancer cells. In such instances, the cells left behind may grow into a new tumor.
Jou explained that TGF-[beta]1 is a double-edged sword because in normal cells it controls cell proliferation and induces apoptosis, however, once the human body suffers from cancer, a high expression of PSPC1 will convert the function of TGF-[beta]1 to promote the survival and growth of
cancer cells.
A Japanese cancer researcher has praised the ongoing human body-centric anime 'Cells at Work!' for accurately portraying how the immune system attacks
cancer cells.
'Bad cholesterol (low-density lipoprotein or LDL) controls the trafficking of tiny vessels which also contain these integrins, and this has huge effects on the ability of
cancer cells to move and spread throughout the body, ' said Thomas Grewal, an associate professor from University of Sydney.
The evidence doesn't come from tests in patients, but on
cancer cells.
The front-line chemotherapy drug paclitaxel sets off a variety of molecular-level changes that allow breast
cancer cells to escape from the tumor.
The research was designed to determine how inhibition of platelet activation through the use of aspirin might affect the proliferation of colon and pancreatic
cancer cells.
As we well know, the "Warburg effect" is the main theory of the energy metabolism in
cancer cells. In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the energy needed for cellular processes, most
cancer cells instead rely on aerobic glycolysis.