| Noun | 1. | calcium-channel blocker - any of a class of drugs that block the flow of the electrolyte calcium (either in nerve cell conduction or smooth muscle contraction of the heart); has been used in the treatment of angina or arrhythmia or hypertension or migraine Cardizem, diltiazem - a calcium blocker (trade name Cardizem) used in treating hypertension or angina or heart failure medicament, medication, medicinal drug, medicine - (medicine) something that treats or prevents or alleviates the symptoms of disease nifedipine, Procardia - calcium blocker (trade name Procardia); appears to increase the risk of recurrent heart attacks |