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Relation between cyclooxygenase-2 expression and tumor invasiveness and patient survival in transitional cell carcinoma of the urinary bladder.

Prognostic significance of CD44, platelet-derived growth factor receptor [alpha], and cyclooxygenase 2 expression in renal cell carcinoma

Role and regulation of cyclooxygenase-2 during inflammation.

Atorvastatin reduces the expression of COX-2 mRNA in peripheral blood monocytes from patients with acute myocardial infarction and modulates the early inflammatory response

Further, the company confirmed that agaro-oligosaccharide can inhibit the generations of cyclooxygenase-2 (COX-2) and prostaglandin E synthase, two enzymes required in the synthesis of prostaglandin E2 (PGE2), which is responsible for inducing inflammation and pains.

Takara Bio Sheds Light on Anti-inflammatory Mechanism of Agaro-oligosaccharide

BOSTON -- Preliminary findings from a prematurely halted trial suggest that osteoarthritis patients may have options beyond cyclooxygenase-2 inhibitors at their disposal for easing their pain.

Lidocaine patch may rival COX-2s for relief of osteoarthritis pain

Before the cyclooxygenase-2 (COX-2) inhibitors were introduced, 14 percent of Canada's population used anti-inflammatory drugs.

Upper GI bleeding hospitalizations and COX-2 drugs

Mount Sinai of Medicine of New York University (New York, NY) has patented transgenic mice whose genomes comprise a gene encoding human cyclooxygenase-2 under the control of a neuron-specific promoter.

Mount Sinai obtains United States patent

In particular, it appears to control levels of a protein called cyclooxygenase-2 (COX-2) which has a direct impact on cancer.

Two new weapons in cancer battle

Cyclooxygenase-2 (Cox-2) inhibitors, such as rofecoxib (Vioxx) and celecoxib (Celebrex), are newer agents that may prove to be safer alternatives to NSAIDs in the treatment of chronic pain.

Chronic pain: we're undertreating the elderly: having read many accounts of undertreatment, this consultant pharmacist mounted his own study. Here's what he found. (Feature Article)

The other key study criteria, including use of endoscopic evaluation rather than symptomatology and study duration, also have been commonly used in studies of cyclooxygenase-2 (COX-2) and NSAIDs.

RISEDRONATE REDUCES INCIDENCE OF GASTRIC ULCERS

Objective: To investigate the expression of cyclooxygenase-2 and cluster of differentiation 95 in renal cell carcinomas having different clinico-pathological characteristics.

Relationship of CD95 and COX-2 in renal cell carcinomas with survival and other prognostic parameters: A tissue microarray study

During inflammation, fibroblasts become activated and produce inflammatory mediators, including interleukin-8 (IL-8), monocyte chemoattractant protein-1, and express cyclooxygenase-2 (COX-2), with the resultant release of proinflammatory prostaglandins (PCs) such as [prostaglandinE.sub.2] ([PGE.sub.2]) [5, 6].

Novel biphasic role of Resolvin D1 on expression of cyclooxygenase-2 in lipopolysaccharide-stimulated lung fibroblasts is partly through PI3K/AKT and ERK2 pathways

PURPOSE: Cyclooxygenase-2 (COX-2) inhibitors hold promise for cancer chemoprevention; however, recent toxicity concerns suggest that new strategies are needed.

Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo